VENTDOX M – Doxofylline 400mg + Montelukast 10mg | Asthma & COPD 10 Tablet

Description

VENTDOX M Tablets (Doxofylline SR 400mg + Montelukast 10mg) – Dual-Action Respiratory Therapy

Category: Bronchodilator + Leukotriene Modulator Combination
Pack Size: 10 Tablets (Sustained-Release)
Active Ingredients:

• Doxofylline SR 400mg (Xanthine bronchodilator)

• Montelukast 10mg (Leukotriene receptor antagonist)

Key Benefits:
✔️ Dual-mechanism action for comprehensive asthma/COPD control
✔️ Sustained-release doxofylline for 24-hour bronchodilation
✔️ Montelukast prevents airway inflammation and bronchoconstriction
✔️ Reduced nighttime symptoms and exercise-induced asthma attacks
✔️ Lower side effect profile compared to theophylline combinations

Approved Uses:
• Bronchial asthma (maintenance treatment)
• Chronic obstructive pulmonary disease (COPD)
• Exercise-induced bronchoconstriction
• Allergic rhinitis with associated asthma

Dosage (Adults ≥15 years):

• 1 tablet once daily in the evening

• Swallow whole with water (do not crush or chew)

• May be taken with or without food

Safety Information:
⚠️ Contraindications:

• Hypersensitivity to xanthine derivatives or montelukast

• Phenylketonuria (montelukast contains aspartame)

• Severe hepatic impairment

⚠️ Monitor For:
• Headache or dizziness (usually transient)
• Gastrointestinal discomfort
• Rare neuropsychiatric reactions (with montelukast)

Drug Interactions:
▲ Significant interactions:

• Phenobarbital/Rifampin (reduces montelukast efficacy)

• Fluoroquinolones (may increase doxofylline levels)

• High-fat meals (delay doxofylline absorption)

Storage Conditions:
• Store below 30°C in original packaging
• Protect from moisture and light