CEFAVIAL SB 375 – Ceftriaxone 250mg+Sulbactam 125mg | Injection

Description

CEFAVIAL SB 375 – Ceftriaxone 250mg + Sulbactam 125mg Powder for Injection (1 Vial) | β-Lactamase Protected Antibiotic

Category: Antibiotic Combination / Cephalosporin + β-Lactamase Inhibitor
Pack Size: 1 Vial (Powder for reconstitution)
Active Ingredients:

• Ceftriaxone Sodium IP 250mg

• Sulbactam Sodium IP 125mg

✅ Key Benefits:

✔ Enhanced activity against resistant bacterial strains
✔ Synergistic action against MDR organisms
✔ Ideal for hospital-acquired infections
✔ Cost-effective alternative to carbapenems

🦠 Approved Uses:

• Complicated intra-abdominal infections

• Nosocomial pneumonia (including ventilator-associated)

• Severe skin/soft tissue infections

• Pelvic inflammatory disease

💉 Dosage Instructions:

• Adults: 1.5-3g daily (1-2 vials every 12 hours)

• IV Administration:

  1. Reconstitute with 2ml sterile water/Lidocaine HCl

  2. Further dilute in 50-100ml NS/D5W

  3. Infuse over 30-60 minutes

• IM Administration:

  • Use 1% Lidocaine as diluent

  • Max 750mg per injection site

⚠️ Critical Warnings:

❌ Contraindicated in:

• Known hypersensitivity to β-lactams

• Neonatal hyperbilirubinemia
  ⚠️ Monitor for:

• Diarrhea (risk of C. difficile colitis)

• Injection site reactions

❄️ Storage:

• Before reconstitution: Below 25°C (protect from light)

• After reconstitution:

  • NS solutions: Stable for 24 hours at 25°C

  • D5W solutions: Stable for 6 hours