CEFAVIAL 1000 – Ceftriaxone 1g Injection (1 Vial) | Hospital Antibiotic

Description

CEFAVIAL 1000 – Ceftriaxone 1g Powder for Injection (1 Vial) | Third-Generation Cephalosporin Antibiotic

Category: Antibiotic Injection / Cephalosporin
Pack Size: 1 Vial (Ceftriaxone Sodium IP 1g)
Active Ingredient: Ceftriaxone Sodium equivalent to Ceftriaxone 1000mg

Key Benefits:
✔ Extended 24-hour dosing interval (single daily dose in most cases)
✔ Excellent CSF penetration for CNS infections
✔ Dual elimination pathway (no renal dose adjustment)
✔ Hospital workhorse for serious infections

Approved Uses:

• Severe sepsis (including neonatal sepsis)

• Meningitis (community-acquired)

• Multidrug-resistant typhoid fever

• Surgical prophylaxis (colorectal/orthopedic)

Dosage Instructions:

• Adults: 1-2g every 24 hours (up to 4g/day in meningitis)

• IV Administration:

  1. Reconstitute with 10ml sterile water (for 100mg/ml)

  2. Further dilute in 50-100ml NS/D5W

  3. Infuse over 30 minutes

• IM Administration:

  • Reconstitute with 3.5ml 1% lidocaine (for pain reduction)

Critical Warnings:
❌ Contraindicated in:

• Cephalosporin/penicillin anaphylaxis

• Hyperbilirubinemic neonates
  ⚠️ May cause:

• Biliary pseudolithiasis (risk with prolonged use)

• Vitamin K deficiency (monitor PT/INR)

Storage:

• Unreconstituted: Below 25°C (protect from light)

• Reconstituted:

  • NS solutions: Stable 3 days at 25°C

  • D5W solutions: Stable 24 hours