COXIFY PG 60/75 – Etoricoxib 60mg + Pregabalin 75mg Tablets (10’s) | Dual-Mechanism Pain Therapy

Description

COXIFY PG 60/75 – Etoricoxib 60mg + Pregabalin 75mg Tablets (10’s) | Dual-Mechanism Pain Therapy
*COX-2 Inhibitor + Neuromodulator for Chronic Pain Conditions*

Category: NSAID + Antineuropathic Combination
Pack Size: 10 Film-Coated Tablets

Composition (Per Tablet):

• Etoricoxib 60mg (Selective COX-2 inhibitor)

• Pregabalin 75mg (Calcium channel modulator)

Key Benefits:
✔️ Comprehensive Pain Control:

• Targets inflammation (Etoricoxib)

• Modulates nerve pain (Pregabalin)
  ✔️ Neuroprotective Action: Reduces central sensitization
  ✔️ GI Advantage: Lower ulcer risk vs traditional NSAIDs
  ✔️ Synergistic Efficacy: Enhanced effect in mixed pain

Approved Indications:
• Chronic low back pain with neuropathic component
• Osteoarthritis with radicular symptoms
• Diabetic neuropathy with inflammation
• Post-herpetic neuralgia
• Fibromyalgia (adjuvant therapy)

Dosage (Adults ≥18 years):

• Standard Dose: 1 tablet twice daily

• Renal Adjustment:

  • CrCl 30-60mL/min: 1 tablet daily

  • CrCl <30mL/min: Contraindicated

• Take With: Food and full glass of water

Safety Profile:
🚫 Absolute Contraindications:

• Severe cardiac failure (NYHA Class IV)

• Angioedema history (pregabalin)

• Third trimester pregnancy

⚠️ Required Monitoring:
• Weight gain (pregabalin effect)
• Mood changes/depression
• Peripheral edema

Drug Interactions:
▲ Critical Interactions:

• ACE inhibitors (↑ angioedema risk)

• CNS depressants (↑ sedation)

• Thiazolidinediones (↑ edema risk)

Storage:
• Below 30°C
• Protect from moisture