CORTIRULE 100 – Hydrocortisone 100mg Injection | Emergency Steroid

Description

CORTIRULE 100 – Hydrocortisone Sodium Succinate 100mg Powder for Injection

(Emergency Steroid for Anaphylaxis & Adrenal Crisis)

Category: Corticosteroid / Glucocorticoid
Pack Size: 1 Single-Dose Vial
Active Ingredient: Hydrocortisone Sodium Succinate IP 100mg (as lyophilized powder)

🟢 Key Benefits

✔ Rapid-onset water-soluble formulation
✔ Multi-route administration (IV bolus/IM/IV infusion)
✔ Critical care essential for life-threatening conditions
✔ Compatible with standard IV solutions (NS/D5W)

🚨 Approved Indications

• Anaphylactic shock (adjunct to epinephrine)

• Acute adrenal insufficiency

• Severe asthma exacerbations

• Acute inflammatory emergencies

💉 Dosage & Administration

Adult Emergency Dosing:

• Anaphylaxis: 100-200mg IV push (over 30 sec)

• Adrenal Crisis: 100mg IV q6-8h

• Infusion: Dilute in 50-100ml NS (run over 15-30 min)

Pediatric Dosing:

• 1-2mg/kg/dose (max 100mg)

Reconstitution:

1. Add 2ml Sterile Water for Injection

2. Swirl gently (DO NOT SHAKE)

3. Use immediately

⚠️ Critical Warnings

❌ Absolute Contraindications:

• Systemic fungal infections

• Cerebral malaria

• Live vaccine administration

⚠️ Monitoring Required:

• Blood glucose (hyperglycemia risk)

• Serum electrolytes (hypokalemia)

• GI bleeding symptoms

🛄 Storage Conditions

• Unreconstituted: Below 25°C (protect from light)

• Reconstituted: Use within 3 hours

📊 Regulatory Status

• WHO Essential Medicine List

• Schedule H Drug (India)

• FDA/EMA Approved