PANWERKE DSR – Pantoprazole 40mg+Domperidone 30mg | 100 Caps

Description

PANWERKE DSR – Pantoprazole 40mg (EC) + Domperidone 30mg (SR) Capsules

Dual-Action Gastroprokinetic PPI for Refractory GERD

Category: PPI + Prokinetic Combination
Pack Size: 10×10 Blisters (100 Capsules)
Composition per Capsule:

• Pantoprazole 40mg (Enteric-coated pellets)

• Domperidone 30mg (Sustained-release beads)

✅ Key Benefits

✔ Dual-mechanism action: Acid suppression + Gastric emptying
✔ SR domperidone: 12-hour prolonged effect
✔ Superior to PPI monotherapy for:

• Nighttime reflux

• Regurgitation-predominant GERD
  ✔ Alu-Alu packing for 36-month stability

🩺 Approved Indications

• Refractory GERD (PPI non-responders)

• Diabetic gastroparesis

• Functional dyspepsia with delayed emptying

• Nausea/vomiting associated with GERD

💊 Dosage Instructions

• Adults: 1 capsule twice daily (before breakfast & dinner)

• Max Duration: 12 weeks (cardiac monitoring advised)

• Administration:

  1. Swallow whole with water

  2. Do not open/crush (EC/SR protection)

  3. Take 30 mins before meals

⚠️ Critical Safety Information

❌ Absolute Contraindications:

• QT prolongation/heart failure

• Concomitant strong CYP3A4 inhibitors

• GI obstruction/perforation

⚠️ Black Box Warning:

• Cardiac arrhythmia risk (especially in >60 years)

⚠️ Monitor for:

• ECG changes (baseline + periodic)

• Galactorrhea (hyperprolactinemia)

🛄 Storage

• Below 30°C (Alu-Alu protects from moisture)

• Keep in original blisters